| Academic Unit: |
Molecular Biology and Genetics |
| Mode of Delivery: |
Face to face |
| Prerequisites: |
None |
| Language of Instruction: |
English |
| Level of Course Unit: |
Undergraduate |
| Course Coordinator: |
- - |
| Course Objectives: |
This course focuses on oxidation-reduction (redox) reactions that play an essential role in health and disease. The effect of oxygen on biological networks will be analyzed. How and where the reactive species are generated will be a concern. Redox homeostasis will be focused. Physiological and pathological processes related to redox will be analyzed. |
| Course Contents: |
Reactive species, ROS generating systems, antioxidants, redox cycling, redox regulation, redox assays |
| Learning Outcomes of the Course Unit (LO): |
- 1- Understanding the importance of reducing power
- 2- Describing reactive species and antioxidants
- 3- Exploring the redox regulation in health and disease
- 4- Analyzing redox-based assays
|
| Planned Learning Activities and Teaching Methods: |
PowerPoint presentations, which are also shared with the students through the KHAS Learn platform, will introduce the concepts. Watching mechanistic/explanatory videos during lectures and discussing with students. Questions integrating the previously covered lectures into ongoing lecture content and discussing to figure out an answer will allow students better understand how the concepts are related to each other. JoVE platform, selected review/ research articles will support the course content and help students review the lecture and visualize the subject. |
| Week | Subjects | Related Preperation |
| 1 |
O2 as a terminal electron acceptor |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 2 |
Reactive species |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 3 |
ROS generating systems |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 4 |
Antioxidant molecules |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 5 |
Antioxidant enzymes |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 6 |
Redox cofactors |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 7 |
Midterm Exam Week: The exact date/time will be announced later. |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 8 |
Redox regulation |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 9 |
Amino acid metabolism |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 10 |
Lipid catabolism |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 11 |
Oxidative stress as a marker |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 12 |
Reductive stress |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 13 |
Redox assays |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
| 14 |
Review |
The students should follow the KHAS Learn pages to examine the assigned material before and after the lecture hours. |
At Kadir Has University, a Semester is 14 weeks; The weeks 15 and 16 are reserved for final exams.
THE RELATIONSHIP BETWEEN COURSE LEARNING OUTCOMES (LO) AND PROGRAM QUALIFICATIONS (PQ)
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PQ11 |
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Contribution: 1 Low, 2 Average, 3 High
