COURSE DESCRIPTION AND APPLICATION INFORMATION
| Course Name | Code | Semester | T+A+L (hour/week) | Type (C / O) | Local Credit | ECTS |
|---|---|---|---|---|---|---|
| Molecular Biophysics | MBG 317 | Fall | 03+00+00 | Elective | 3 | 5 |
| Academic Unit: | Molecular Biology and Genetics |
| Mode of Delivery: | Face to face |
| Prerequisites: | - |
| Language of Instruction: | English |
| Level of Course Unit: | Undergraduate |
| Course Coordinator: | - - |
| Course Objectives: | This course aims to introduce the students to spectroscopic methods and to teach them how to apply these methods to real biological systems by performing experiments and carry out two major projects on the topic |
| Course Contents: | Introduction to spectroscopy for the Biological Sciences. UV-vis spectrophotometer and electronic spectra. Vibration in macromolecules
Magnetic resonance. X-ray crystallography. Mass spectrometry. Raman Spectroscopy. Circular dichroism and optical rotary dispersion |
| Learning Outcomes of the Course Unit (LO): |
|
| Planned Learning Activities and Teaching Methods: | Lectures, student presentations, thematic assignments, and laboratory work. Project work. |
WEEKLY SUBJECTS AND RELATED PREPARATIONS
| Week | Subjects | Related Preperation |
|---|---|---|
| 1 | Introduction to spectroscopy for the Biological Sciences. | Presentation, project |
| 2 | UV-vis spectrophotometer and electronic spectra. | Presentation, project |
| 3 | UV-vis spectrophotometer and electronic spectra. | Presentation, project |
| 4 | Vibration in macromolecules | Presentation, project |
| 5 | Vibration in macromolecules | Presentation, project |
| 6 | Magnetic resonance. | Presentation, project |
| 7 | X-ray crystallography. | Presentation, project |
| 8 | X-ray crystallography. | Presentation, project |
| 9 | Mass spectrometry | Presentation, project |
| 10 | Mass spectrometry | Presentation, project |
| 11 | Raman Spectroscopy. | Presentation, project |
| 12 | Raman Spectroscopy. | Presentation, project |
| 13 | Circular dichroism and optical rotary dispersion | Presentation, project |
| 14 | Circular dichroism and optical rotary dispersion | Presentation, project |
At Kadir Has University, a Semester is 14 weeks; The weeks 15 and 16 are reserved for final exams.
REQUIRED AND RECOMMENDED READING
| E-books: •Biomolecular Nmr Spectroscopy, Dingley, A. J, Pascal, Steven M., Dingley, Andrew J., IEEE, 2011. •Optical Spectroscopy: Technology, Properties and Performance, Tomozeiu, Nicolae, New York : Nova Science Publishers, Inc. 2014. •Spectroscopy of Biological Molecules : Proceedings From the 14th European Conference on the Spectroscopy of Biological Molecules, Haris, P. I., Carvalho, Luís A. E. Batista de, Marques, Maria Paula, IOS Press, 2011. •Infrared and Raman Spectroscopy: Principles and Spectral Interpretation, Peter Larkin. Amsterdam: Elsevier. 2011 Spectroscopy for the Biological Sciences, Gordon G. Hammes, Wiley Inc., 2005 Principles of Physical Biochemistry, van Holde, Johnson & Ho, 2006 |
OTHER COURSE RESOURCES
| Biophysical Chemistry, Cantor & Schimmel, I-III, 1980 Elementary Biophysics: An Introduction, P. K. Srivastava Physics for the Biological Sciences, Hallett Molecular and Cellular Biophysics, Meyer B Jackson, 2006, Cambridge Physical Chemistry for the Biosciences, Raymond Chang, 2004 “Biological Physics: Energy, Information, Life” P. Nelson, Freeman, 2008 |
ASSESSMENT METHODS AND CRITERIA
| Semester Requirements | Number | Percentage of Grade (%) |
|---|---|---|
| Attendance / Participation | 14 | - |
| Project | 1 | 20 |
| Homework Assignments | 5 | 40 |
| Presentation / Jury | 1 | 5 |
| Other Practices (seminar, studio critics, workshop etc.) | 1 | 35 |
| Total: | 22 | 100 |
WORKLOAD
| Events | Count | Duration (Hours) | Total Workload (hour) |
|---|---|---|---|
| Course Hours | 14 | 3 | 42 |
| Project | 1 | 28 | 28 |
| Homework Assigments | 5 | 10 | 50 |
| Other Practices (seminar,studio critics,workshop, etc.) | 1 | 5 | 5 |
| Total Workload (hour): | 125 | ||
1 ECTS = 25 Hours Workload
THE RELATIONSHIP BETWEEN COURSE LEARNING OUTCOMES (LO) AND PROGRAM QUALIFICATIONS (PQ)
| # | PQ1 | PQ2 | PQ3 | PQ4 | PQ5 | PQ6 | PQ7 | PQ8 | PQ9 | PQ10 | PQ11 | PQ12 |
| LO1 | ||||||||||||
| LO2 | ||||||||||||
| LO3 | ||||||||||||
| LO4 | ||||||||||||
| LO5 |
Contribution: 1 Low, 2 Average, 3 High